Bonnie Mitchell
ON THE RECORD · 12 verbatim quotes · every quote source-verified
“If a patient develops emergent depression or suicidal ideation during treatment, clinicians should discontinue the weight-loss medication and connect the patient with psychiatric support.”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell stated that if a patient develops emergent depression or suicidal ideation during treatment, clinicians should discontinue the weight-loss medication and provide psychiatric support.
“Any active suicidal thoughts require immediate emergency medical care.”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell repeated her advice that any active suicidal thoughts require immediate emergency medical care.
“The study highlighted a striking sub finding that found users who gained weight despite taking the medication had 4.2 times higher odds of suicidal ideation compared to non-users,”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell highlighted a study finding that users who gained weight despite taking medication had 4.2 times higher odds of suicidal ideation compared to non-users.
“Doctors can inform patients and caregivers about potential mood changes so they know what to watch for,”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell recommended that doctors inform patients and caregivers about potential mood changes to watch for.
“It shows a correlation between weight-loss drug use and self-reported mental health symptoms, but it cannot prove causation,”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell told Fox News Digital that the observational, cross-sectional study shows a correlation but cannot prove causation.
“Even though GLP-1 clinical trials show low absolute risk, the FDA’s product labels for chronic weight management drugs (like Wegovy and Zepbound) include warnings to monitor for mood changes,”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell noted that FDA product labels for chronic weight management drugs like Wegovy and Zepbound include warnings to monitor for mood changes.
“The next important step for ongoing monitoring would be to schedule check-ins at 4- to 8-week intervals during dose escalation, to evaluate both physiological progress and psychological well-being.”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell recommended scheduling check-ins at 4- to 8-week intervals during dose escalation to evaluate physiological and psychological well-being.
“The study sample captures older anti-obesity agents historically prescribed in South Korea during that decade, including phentermine, diethylpropion, phendimetrazine, topiramate and orlistat.”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell explained that the study sample reflects older anti-obesity agents commonly prescribed in South Korea during the prior decade.
“Individuals with severe obesity have higher baseline rates of depression, anxiety and body dysmorphia.”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell repeated that individuals with severe obesity have higher baseline rates of depression, anxiety and body dysmorphia.
“A cross-sectional survey cannot separate pre-existing mental health struggles from new symptoms that arose after starting a medication.”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell stated that a cross-sectional survey cannot distinguish pre-existing mental health struggles from new symptoms arising after starting a medication.
“During most of this period, modern GLP-1/GIP receptor agonists used for weight loss (such as high-dose semaglutide/Wegovy or tirzepatide/Zepbound/Mounjaro) were either not yet on the market or had very limited real world uptake in South Korea,”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell noted that modern GLP-1/GIP receptor agonists had limited availability in South Korea during the 2013–2022 data collection period.
“It does not demonstrate that weight-loss medications directly induce depression or suicidal thoughts.”
Bonnie Mitchell · said date not stated · reported 2026-09-09
Mitchell told Fox News Digital the study does not demonstrate that weight-loss medications directly cause depression or suicidal thoughts.