“DNA double-strand breaks are like a rope snapping completely in two, rather than just fraying at the edges. We found that KCL-286 promotes repair of these breaks, allowing us to target a key feature of Alzheimer's disease,”

Jonathan Corcoran · said date not stated · reported 2026-11-03

Professor Corcoran explained that KCL-286 promotes repair of DNA double-strand breaks, a key feature of Alzheimer's disease.